Anti-Human PTK2B/PYK2 Recombinant Antibody (12A10), PE (HC433127)

Name: Anti-Human PTK2B/PYK2 Recombinant Antibody (12A10), PE
Brand: abinScience
SKU: HC433127
Price: 290 USD
Availability: InStock

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Número de catálogo	HC433127
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a
ID de clon	12A10
Conjugación	PE
Objetivo	Protein-tyrosine kinase 2-beta, 2.7.10.2, Calcium-dependent tyrosine kinase, CADTK, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, CAK-beta, CAKB, Focal adhesion kinase 2, FADK 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, RAFTK, PTK2B, FAK2, PYK2, RAFTK
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PE
Número de acceso	Q14289
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Protein-tyrosine kinase 2-beta (PTK2B/PYK2) is a ~115 kDa protein. Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC.
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human PTK2B/PYK2 Recombinant Antibody (12A10), PE.pdf

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