Anti-Human PTK2B/PYK2 Recombinant Antibody (12A10), PerCP (HC433147)

Name: Anti-Human PTK2B/PYK2 Recombinant Antibody (12A10), PerCP
Brand: abinScience
SKU: HC433147
Price: 268 USD
Availability: InStock

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Overview

Catalog No.	HC433147
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG2a
Clone ID	12A10
Conjugation	PerCP
Clonality	Monoclonal
Target	Protein-tyrosine kinase 2-beta, 2.7.10.2, Calcium-dependent tyrosine kinase, CADTK, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, CAK-beta, CAKB, Focal adhesion kinase 2, FADK 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, RAFTK, PTK2B, FAK2, PYK2, RAFTK
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PerCP
Accession	Q14289
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Protein-tyrosine kinase 2-beta (PTK2B/PYK2) is a ~115 kDa protein. Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human PTK2B/PYK2 Recombinant Antibody (12A10), PerCP.pdf

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Anti-Human PTK2B/PYK2 Recombinant Antibody (12A10), PerCP (HC433147)

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