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Anti-Human PTPN23 Polyclonal Antibody (HP742014)

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Vista general
Número de catálogoHP742014
Descripción
Anti-Human PTPN23 Polyclonal Antibody (HP742014) is a rabbit polyclonal antibody detecting PTPN23 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PTPN23 (Met1-His321).
Objetivo KIAA1471, PTPN23, PTP-TD14, His domain-containing protein tyrosine phosphatase, HD-PTP, Tyrosine-protein phosphatase non-receptor type 23, Protein tyrosine phosphatase TD14
Purificación Purified by antigen affinity column.
Número de acceso Q9H3S7
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Tyrosine-protein phosphatase non-receptor type 23 (PTPN23) is a ~178 kDa protein. Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

1. Doyotte, A. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6308-13. PMID: 18434552
2. Stefani, F. et al. (2011) Current biology : CB 21, 1245-50. PMID: 21757351
3. Kim, J. et al. (2010) Nature 464, 1048-51. PMID: 20393563
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human PTPN23 Polyclonal Antibody

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