Anti-Human PTPN23 Polyclonal Antibody (HP742024)

Name: Anti-Human PTPN23 Polyclonal Antibody
Brand: abinScience
SKU: HP742024
Price: 96 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HP742024

Description

Anti-Human PTPN23 Polyclonal Antibody (HP742024) is a rabbit polyclonal antibody detecting PTPN23 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human PTPN23 (His21-His321).

Target

PTPN23

Purification

Purified by antigen affinity column.

Accession

Q9H3S7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Tyrosine-protein phosphatase non-receptor type 23, 3.1.3.48, His domain-containing protein tyrosine phosphatase, HD-PTP, Protein tyrosine phosphatase TD14, PTP-TD14, PTPN23, KIAA1471

Background

Tyrosine-protein phosphatase non-receptor type 23 (PTPN23) is a ~178 kDa protein. Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

1. Doyotte, A. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6308-13. PMID: 18434552

2. Stefani, F. et al. (2011) Current biology : CB 21, 1245-50. PMID: 21757351

3. Kim, J. et al. (2010) Nature 464, 1048-51. PMID: 20393563

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-PTPN23 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate

References

Datasheet

Anti-Human PTPN23 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PTPN23 Polyclonal Antibody (HP742024)

Overview

Images

References

Datasheet

SDS

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