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| カタログ番号 | HP742014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human PTPN23 Polyclonal Antibody (HP742014) is a rabbit polyclonal antibody detecting PTPN23 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PTPN23 (Met1-His321). | ||||||||
| ターゲット | KIAA1471, PTPN23, PTP-TD14, His domain-containing protein tyrosine phosphatase, HD-PTP, Tyrosine-protein phosphatase non-receptor type 23, Protein tyrosine phosphatase TD14 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9H3S7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tyrosine-protein phosphatase non-receptor type 23 (PTPN23) is a ~178 kDa protein. Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis. 1. Doyotte, A. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6308-13. PMID: 18434552 2. Stefani, F. et al. (2011) Current biology : CB 21, 1245-50. PMID: 21757351 3. Kim, J. et al. (2010) Nature 464, 1048-51. PMID: 20393563 | ||||||||
| 注意事項 | For research use only. |
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