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Anti-Human RAB10 Recombinant Antibody (SAA1654)
Anti-Human RAB10 Recombinant Antibody (SAA1654)
Цена(USD):
Спецификация:
  • 50ug
  • 100ug
  • 1mg
Количество:
Свяжитесь с нами
  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHX991013
Реактивность видовHuman
ПримененияELISA
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG2a, kappa
ID клонаSAA1654
Цель Ras-related protein Rab-10, RAB10
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P61026
RRID Anti-Human RAB10 Antibody (SAA1654) (abinScience Cat# HX991013, RRID:AB_3727415)
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

Ras-related protein Rab-10 (RAB10) is a ~22 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB10 is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, RAB10 regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response.

1. Hutagalung, AH. et al. (2011) Physiological reviews 91, 119-49. PMID: 21248164
2. Babbey, CM. et al. (2006) Molecular biology of the cell 17, 3156-75. PMID: 16641372
3. English, AR. et al. (2013) Nature cell biology 15, 169-78. PMID: 23263280
4. Dhekne, HS. et al. (2018) eLife 7. PMID: 30398148
5. Lucken-Ardjomande Häsler, S. et al. (2020) The Journal of cell biology 219. PMID: 32344433
6. Eguchi, T. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E9115-E9124. PMID: 30209220
Примечание For research use only.
Изображения
  • Anti-Human RAB10 Recombinant Antibody (SAA1654)

    SDS-PAGE

    SDS-PAGE for Anti-Human RAB10 Antibody (SAA1654)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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