Anti-Human RAMP3 Recombinant Antibody (SAA1504) (HF617013)

Name: Anti-Human RAMP3 Recombinant Antibody (SAA1504)
Brand: abinScience
SKU: HF617013
Price: 110 USD
Availability: InStock

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1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF617013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1504

Cible

Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, RAMP3, CRLR activity-modifying protein 3

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O60896

RRID

Anti-Human RAMP3 Antibody (SAA1504) (abinScience Cat# HF617013, RRID:AB_3727265)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Receptor activity-modifying protein 3 (RAMP3) is a ~16 kDa protein. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1). Required for the transport of CALCRL and GPER1 receptors to the plasma membrane. Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2. Together with CALCR, act as a receptor complex for amylin/IAPP.

1. Lenhart, PM. et al. (2013) Journal of molecular endocrinology 51, 191-202. PMID: 23674134

2. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797

3. Liang, YL. et al. (2020) ACS pharmacology & translational science 3, 263-284. PMID: 32296767

4. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Human RAMP3 Antibody (SAA1504).

Reférences

Fiche technique

Anti-Human RAMP3 Recombinant Antibody (SAA1504).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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