Anti-Human RAMP3 Recombinant Antibody (SAA2365) (HF617023)

Name: Anti-Human RAMP3 Recombinant Antibody (SAA2365)
Brand: abinScience
SKU: HF617023
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF617023

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA2365

Clonality

Monoclonal

Target

Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O60896

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Receptor activity-modifying protein 3 (RAMP3) is a ~16 kDa protein. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1). Required for the transport of CALCRL and GPER1 receptors to the plasma membrane. Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2. Together with CALCR, act as a receptor complex for amylin/IAPP.

1. Lenhart, PM. et al. (2013) Journal of molecular endocrinology 51, 191-202. PMID: 23674134

2. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797

3. Liang, YL. et al. (2020) ACS pharmacology & translational science 3, 263-284. PMID: 32296767

4. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Human RAMP3 Antibody (SAA2365)

References

Datasheet

Anti-Human RAMP3 Recombinant Antibody (SAA2365).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RAMP3 Recombinant Antibody (SAA2365) (HF617023)

Overview

Images

References

Datasheet

SDS

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