Anti-Human RAMP3 Recombinant Antibody (SAA1504) (HF617013)

Name: Anti-Human RAMP3 Recombinant Antibody (SAA1504)
Brand: abinScience
SKU: HF617013
Price: 110 USD
Availability: InStock

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Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HF617013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1504

Цель

Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, RAMP3, CRLR activity-modifying protein 3

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

O60896

RRID

Anti-Human RAMP3 Antibody (SAA1504) (abinScience Cat# HF617013, RRID:AB_3727265)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Receptor activity-modifying protein 3 (RAMP3) is a ~16 kDa protein. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1). Required for the transport of CALCRL and GPER1 receptors to the plasma membrane. Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2. Together with CALCR, act as a receptor complex for amylin/IAPP.

1. Lenhart, PM. et al. (2013) Journal of molecular endocrinology 51, 191-202. PMID: 23674134

2. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797

3. Liang, YL. et al. (2020) ACS pharmacology & translational science 3, 263-284. PMID: 32296767

4. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283

Примечание

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human RAMP3 Antibody (SAA1504).

Ссылки

Даташит

Anti-Human RAMP3 Recombinant Antibody (SAA1504).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа