Anti-Human RB1CC1 Polyclonal Antibody (HP312014)

Name: Anti-Human RB1CC1 Polyclonal Antibody
Brand: abinScience
SKU: HP312014
Price: 168 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD):

Спецификация:

50ug
100ug

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HP312014

Описание

Anti-Human RB1CC1 Polyclonal Antibody (HP312014) is a rabbit polyclonal antibody detecting RB1CC1 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human RB1CC1 (Glu1447-Val1594).

Цель

FAK family kinase-interacting protein of 200 kDa, RB1CC1, FIP200, RBICC, RB1-inducible coiled-coil protein 1, KIAA0203

Очистка

Purified by antigen affinity column.

Номер доступа

Q8TDY2

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

RB1-inducible coiled-coil protein 1 (RB1CC1) is a ~183 kDa protein. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways.

1. Morselli, E. et al. (2011) Cell cycle (Georgetown, Tex.) 10, 2763-9. PMID: 21775823

2. Nishimura, T. et al. (2013) EMBO reports 14, 284-91. PMID: 23392225

3. Ueda, H. et al. (2000) The Journal of cell biology 149, 423-30. PMID: 10769033

4. Abbi, S. et al. (2002) Molecular biology of the cell 13, 3178-91. PMID: 12221124

5. Chano, T. et al. (2002) Gene 291, 29-34. PMID: 12095676

6. Kontani, K. et al. (2003) International journal of molecular medicine 12, 767-9. PMID: 14533007

7. Chano, T. et al. (2002) The American journal of pathology 161, 359-64. PMID: 12163359

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human RB1CC1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа