Anti-Human RHOA Polyclonal Antibody (HX184014)

Name: Anti-Human RHOA Polyclonal Antibody
Brand: abinScience
SKU: HX184014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HX184014

Descripción

Anti-Human RHOA Polyclonal Antibody (HX184014) is a rabbit polyclonal antibody detecting RHOA in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human RHOA (Ala2-Gly189).

Objetivo

Rho cDNA clone 12, ARH12, RHO12, ARHA, RHOA, Transforming protein RhoA, h12

Purificación

Purified by antigen affinity column.

Número de acceso

P61586

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Transforming protein RhoA is a ~21 kDa protein. Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such as cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation.

1. Wei, J. et al. (2013) Biochimica et biophysica acta 1833, 2757-2764. PMID: 23871831

2. Vabres, P. et al. (2019) Nature genetics 51, 1438-1441. PMID: 31570889

3. Quilliam, LA. et al. (1996) The Journal of biological chemistry 271, 28772-6. PMID: 8910519

4. Vincent, S. et al. (1997) Molecular and cellular biology 17, 2247-56. PMID: 9121475

5. Wing, MR. et al. (2003) The Journal of biological chemistry 278, 41253-8. PMID: 12900402

6. Kamijo, K. et al. (2006) Molecular biology of the cell 17, 43-55. PMID: 16236794

7. Wallace, SW. et al. (2011) Molecular and cellular biology 31, 81-91. PMID: 20974804

8. Dubash, AD. et al. (2013) The Journal of cell biology 202, 653-66. PMID: 23940119

9. Bristow, JM. et al. (2009) Journal of cell science 122, 4535-46. PMID: 19934221

10. Zaoui, K. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 18517-22. PMID: 20937854

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human RHOA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo