Anti-Human ROR1 Recombinant Antibody (SAA0140) (HX065107)

Name: Anti-Human ROR1 Recombinant Antibody (SAA0140)
Brand: abinScience
SKU: HX065107
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	HX065107
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, Kappa
ID de clon	SAA0140
Aplicaciones probadas	FCM
Objetivo	Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1, UC-961
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q01973
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling. 1. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443 2. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350 3. Lin, W. et al. (2023) Nature communications 14, 1578. PMID: 36949068
Nota	For research use only.

Imágenes

Flow Cytometry

Flow-cytometry using anti-human ROR1 antibody. Human CACO-2 cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human ROR1 antibody monoclonal antibody (Catalog # HX065107 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414 ) and cells analysed on a NovoCyte Flow Cytometer.

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Datasheet