Anti-Human ROR2/NTRKR2 Recombinant Antibody (GK-5A1) (HX930107)

Name: Anti-Human ROR2/NTRKR2 Recombinant Antibody (GK-5A1)
Brand: abinScience
SKU: HX930107
Price: 191 USD
Availability: InStock

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概要
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参考文献
データシート
SDS

概要

カタログ番号	HX930107
ブランド	abinScience
種反応性	Human, Mouse, Monkey
アプリケーション	ELISA, FCM
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	GK-5A1
ターゲット	ROR2, Neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q01974
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Tyrosine-protein kinase transmembrane receptor ROR2 (NTRKR2) is a ~104 kDa protein. Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. 1. Liu, Y. et al. (2007) Molecular endocrinology (Baltimore, Md.) 21, 3050-61. PMID: 17717073 2. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443
注意事項	For research use only.

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Bioactivity

Detects ROR2/NTRKR2 in indirect ELISAs.
Flow CytoMetry

Flow-cytometry using anti-human ROR2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human ROR2 monoclonal antibody (Catalog: HX930107) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.