Anti-Human SAMTOR Polyclonal Antibody (HD581014)

Name: Anti-Human SAMTOR Polyclonal Antibody
Brand: abinScience
SKU: HD581014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HD581014

Description

Anti-Human SAMTOR Polyclonal Antibody (HD581014) is a rabbit polyclonal antibody detecting SAMTOR. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SAMTOR (Glu34-Asn354).

Cible

BMT2, C7orf60, EC:2.1.1.-, Probable methyltransferase BMT2 homolog, S-adenosylmethionine sensor upstream of mTORC1, SAMTOR

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q1RMZ1

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

S-adenosylmethionine sensor upstream of mTORC1 (SAMTOR) is a ~46 kDa protein. S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase (Potential).

1. Gu, X. et al. (2017) Science (New York, N.Y.) 358, 813-818. PMID: 29123071

2. Tang, X. et al. (2022) Science advances 8, eabn3868. PMID: 35776786

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human SAMTOR Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human SAMTOR Polyclonal Antibody (HD581014)

Aperçu

Images

Reférences

Fiche technique

SDS