Anti-Human SKB1/PRMT5 IP Recombinant Antibody (SAA0228) (HT245013)

Name: Anti-Human SKB1/PRMT5 IP Recombinant Antibody (SAA0228)
Brand: abinScience
SKU: HT245013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HT245013

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IF, IP

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG1

ID de clon

SAA0228

Objetivo

PRMT5, SKB1 homolog, 72 kDa ICln-binding protein, Jak-binding protein 1, Histone-arginine N-methyltransferase PRMT5, SKB1Hs, JBP1, Shk1 kinase-binding protein 1 homolog, SKB1, HRMT1L5, IBP72, Protein arginine N-methyltransferase 5

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

O14744

RRID

Anti-Human SKB1/PRMT5 IP Antibody (SAA0228) (abinScience Cat# HT245013, RRID:AB_3729762)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Protein arginine N-methyltransferase 5 (SKB1/PRMT5) is a ~72 kDa protein. Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. May methylate the N-terminal region of MBD2. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro.

1. Pollack, BP. et al. (1999) The Journal of biological chemistry 274, 31531-42. PMID: 10531356

2. Rho, J. et al. (2001) The Journal of biological chemistry 276, 11393-401. PMID: 11152681

3. Meister, G. et al. (2001) Current biology : CB 11, 1990-4. PMID: 11747828

4. Meister, G. et al. (2002) The EMBO journal 21, 5853-63. PMID: 12411503

5. Jiang, W. et al. (2005) Biochemical and biophysical research communications 329, 522-30. PMID: 15737618

6. Gonsalvez, GB. et al. (2007) The Journal of cell biology 178, 733-40. PMID: 17709427

7. Ren, J. et al. (2010) The Journal of biological chemistry 285, 12695-705. PMID: 20159986

8. Guo, S. et al. (2010) The Journal of biological chemistry 285, 35133-41. PMID: 20810653

9. Guderian, G. et al. (2011) The Journal of biological chemistry 286, 1976-86. PMID: 21081503

10. Hsu, JM. et al. (2011) Nature cell biology 13, 174-81. PMID: 21258366

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human SKB1/PRMT5 IP Antibody (SAA0228)

Referencias

Datasheet

Anti-Human SKB1/PRMT5 IP Recombinant Antibody (SAA0228).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo