Anti-Human SLC15A4 Recombinant Antibody (SAA2356) (HC091023)

Name: Anti-Human SLC15A4 Recombinant Antibody (SAA2356)
Brand: abinScience
SKU: HC091023
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC091023

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG

ID de clon

SAA2356

Objetivo

Solute carrier family 15 member 4, Peptide transporter 4, Peptide/histidine transporter 1, hPHT1, SLC15A4, PHT1, PTR4

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q8N697

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Solute carrier family 15 member 4 (SLC15A4) is a ~62 kDa protein. Proton-coupled amino-acid transporter that mediates the transmembrane transport of L-histidine and some di- and tripeptides from inside the lysosome to the cytosol, and plays a key role in innate immune response. Preferably binds to short peptides with a basic residue at the first position and a hydrophobic residue at the second position. Able to transport a variety of di- and tripeptides, including carnosine and some peptidoglycans. Transporter activity is pH-dependent and maximized in the acidic lysosomal environment. Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand, and L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate (tri-DAP), the NOD1 ligand.

1. Bhardwaj, RK. et al. (2006) European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 27, 533-42. PMID: 16289537

2. Kobayashi, T. et al. (2014) Immunity 41, 375-388. PMID: 25238095

3. Song, F. et al. (2018) Molecular pharmaceutics 15, 385-393. PMID: 29224352

4. Zhang, Z. et al. (2025) Structure (London, England : 1993) 33, 330-337.e4. PMID: 39719710

5. Oppermann, H. et al. (2019) Amino acids 51, 999-1008. PMID: 31073693

6. Heinz, LX. et al. (2020) Nature 581, 316-322. PMID: 32433612

Nota

For research use only

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human SLC15A4 Antibody (SAA2356)

Referencias

Datasheet

Anti-Human SLC15A4 Recombinant Antibody (SAA2356).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo