Anti-Human SLC15A4 Recombinant Antibody (SAA2355) (HC091013)

Name: Anti-Human SLC15A4 Recombinant Antibody (SAA2355)
Brand: abinScience
SKU: HC091013
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC091013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG

Clone ID

SAA2355

Clonality

Monoclonal

Target

Solute carrier family 15 member 4, Peptide transporter 4, Peptide/histidine transporter 1, hPHT1, SLC15A4, PHT1, PTR4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8N697

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Solute carrier family 15 member 4 (SLC15A4) is a ~62 kDa protein. Proton-coupled amino-acid transporter that mediates the transmembrane transport of L-histidine and some di- and tripeptides from inside the lysosome to the cytosol, and plays a key role in innate immune response. Preferably binds to short peptides with a basic residue at the first position and a hydrophobic residue at the second position. Able to transport a variety of di- and tripeptides, including carnosine and some peptidoglycans. Transporter activity is pH-dependent and maximized in the acidic lysosomal environment. Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand, and L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate (tri-DAP), the NOD1 ligand.

1. Bhardwaj, RK. et al. (2006) European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 27, 533-42. PMID: 16289537

2. Kobayashi, T. et al. (2014) Immunity 41, 375-388. PMID: 25238095

3. Song, F. et al. (2018) Molecular pharmaceutics 15, 385-393. PMID: 29224352

4. Zhang, Z. et al. (2025) Structure (London, England : 1993) 33, 330-337.e4. PMID: 39719710

5. Oppermann, H. et al. (2019) Amino acids 51, 999-1008. PMID: 31073693

6. Heinz, LX. et al. (2020) Nature 581, 316-322. PMID: 32433612

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Human SLC15A4 Antibody (SAA2355)

References

Datasheet

Anti-Human SLC15A4 Recombinant Antibody (SAA2355).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC15A4 Recombinant Antibody (SAA2355) (HC091013)

Overview

Images

References

Datasheet

SDS

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