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Anti-Human SLC16A2 Polyclonal Antibody (HW839014)

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Aperçu
Numéro de catalogueHW839014
Description
Anti-Human SLC16A2 Polyclonal Antibody (HW839014) is a rabbit polyclonal antibody detecting SLC16A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human SLC16A2 (Tyr280-Arg322).
Cible Monocarboxylate transporter 7, MCT 8, SLC16A2, MCT 7, MCT8, X-linked PEST-containing transporter, XPCT, Monocarboxylate transporter 8, Solute carrier family 16 member 2
Purification Purified by antigen affinity column.
Numéro d'accès P36021
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Monocarboxylate transporter 8 (SLC16A2) is a ~59 kDa protein. Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable).

1. Friesema, EC. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 2761-72. PMID: 16887882
2. Friesema, EC. et al. (2008) Molecular endocrinology (Baltimore, Md.) 22, 1357-69. PMID: 18337592
3. Kinne, A. et al. (2010) The Journal of biological chemistry 285, 28054-63. PMID: 20628049
4. Kersseboom, S. et al. (2013) Molecular endocrinology (Baltimore, Md.) 27, 801-13. PMID: 23550058
5. Armour, CM. et al. (2015) PloS one 10, e0139343. PMID: 26426690
6. Novara, F. et al. (2017) Human mutation 38, 260-264. PMID: 27805744
7. Groeneweg, S. et al. (2019) Thyroid : official journal of the American Thyroid Association 29, 1499-1510. PMID: 31436139
8. Vatine, GD. et al. (2017) Cell stem cell 20, 831-843.e5. PMID: 28526555
Note For research use only.
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Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SLC16A2 Polyclonal Antibody

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