Human SLC16A2 Recombinant Protein (N-GST & C-His) (HW839022)

Name: Human SLC16A2 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HW839022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HW839022
Description	Recombinant Human SLC16A2 Protein, N-GST & C-His (HW839022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P36021
Protein length	Tyr280-Arg322
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	MCT 7, MCT 8, MCT7, MCT8, Monocarboxylate transporter 7, Monocarboxylate transporter 8, SLC16A2, Solute carrier family 16 member 2, X-linked PEST-containing transporter, XPCT
Background	Monocarboxylate transporter 8 is a ~59 kDa protein. Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable). 1. Friesema, EC. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 2761-72. PMID: 16887882 2. Friesema, EC. et al. (2008) Molecular endocrinology (Baltimore, Md.) 22, 1357-69. PMID: 18337592 3. Kinne, A. et al. (2010) The Journal of biological chemistry 285, 28054-63. PMID: 20628049 4. Kersseboom, S. et al. (2013) Molecular endocrinology (Baltimore, Md.) 27, 801-13. PMID: 23550058 5. Armour, CM. et al. (2015) PloS one 10, e0139343. PMID: 26426690 6. Novara, F. et al. (2017) Human mutation 38, 260-264. PMID: 27805744 7. Groeneweg, S. et al. (2019) Thyroid : official journal of the American Thyroid Association 29, 1499-1510. PMID: 31436139 8. Vatine, GD. et al. (2017) Cell stem cell 20, 831-843.e5. PMID: 28526555
Note	For research use only

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Datasheet

Human SLC16A2 Recombinant Protein (N-GST & C-His).pdf

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Human SLC16A2 Recombinant Protein (N-GST & C-His) (HW839022)

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