Anti-Human SLC16A2 Polyclonal Antibody (HW839014)

Name: Anti-Human SLC16A2 Polyclonal Antibody
Brand: abinScience
SKU: HW839014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HW839014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC16A2 (Tyr280-Arg322).

Target

Monocarboxylate transporter 7, MCT 8, SLC16A2, MCT 7, MCT8, X-linked PEST-containing transporter, XPCT, Monocarboxylate transporter 8, Solute carrier family 16 member 2

Purification

Purified by antigen affinity column.

Accession

P36021

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Monocarboxylate transporter 8 (SLC16A2) is a ~59 kDa protein. Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable).

1. Friesema, EC. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 2761-72. PMID: 16887882

2. Friesema, EC. et al. (2008) Molecular endocrinology (Baltimore, Md.) 22, 1357-69. PMID: 18337592

3. Kinne, A. et al. (2010) The Journal of biological chemistry 285, 28054-63. PMID: 20628049

4. Kersseboom, S. et al. (2013) Molecular endocrinology (Baltimore, Md.) 27, 801-13. PMID: 23550058

5. Armour, CM. et al. (2015) PloS one 10, e0139343. PMID: 26426690

6. Novara, F. et al. (2017) Human mutation 38, 260-264. PMID: 27805744

7. Groeneweg, S. et al. (2019) Thyroid : official journal of the American Thyroid Association 29, 1499-1510. PMID: 31436139

8. Vatine, GD. et al. (2017) Cell stem cell 20, 831-843.e5. PMID: 28526555

Note

For research use only.

Images

References

Datasheet

Anti-Human SLC16A2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC16A2 Polyclonal Antibody (HW839014)

Overview

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References

Datasheet

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