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| カタログ番号 | HC155035 |
|---|---|
| 説明 |
Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A711) [1A711] (HC155035) is a mouse monoclonal antibody detecting SLC22A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, IHC, WB |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | 1A711 |
| 免疫原 | E. coli - derived recombinant human SLC22A2/OCT2 (Gly44-Asp150). |
| ターゲット | Solute carrier family 22 member 2, Organic cation transporter 2, hOCT2, SLC22A2 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | O15244 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Solute carrier family 22 member 2 (SLC22A2/OCT2) is a ~62 kDa protein. Electrogenic voltage-dependent transporter that mediates the transport of a variety of organic cations such as endogenous bioactive amines, cationic drugs and xenobiotics. Functions as a Na(+)-independent, bidirectional uniporter. Cation cellular uptake or release is driven by the electrochemical potential, i.e. membrane potential and concentration gradient. However, may also engage electroneutral cation exchange when saturating concentrations of cation substrates are reached. 1. Gorboulev, V. et al. (1997) DNA and cell biology 16, 871-81. PMID: 9260930 2. Busch, AE. et al. (1998) Molecular pharmacology 54, 342-52. PMID: 9687576 3. Winter, TN. et al. (2011) Molecular pharmaceutics 8, 133-42. PMID: 21128598 4. Urakami, Y. et al. (2004) Pharmaceutical research 21, 976-81. PMID: 15212162 5. Kimura, N. et al. (2005) Pharmaceutical research 22, 255-9. PMID: 15783073 6. Amphoux, A. et al. (2006) Neuropharmacology 50, 941-52. PMID: 16581093 7. Taubert, D. et al. (2007) PloS one 2, e385. PMID: 17460754 |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A711)
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