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Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709) (HC155015)

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Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709)
Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709)
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Overview
Catalog No.HC155015
Description
Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709) [1A709] (HC155015) is a mouse monoclonal antibody detecting SLC22A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
IsotypeIgG
Clone ID1A709
Clonality Monoclonal
Immunogen E. coli - derived recombinant human SLC22A2/OCT2 (Gly44-Asp150).
Target Solute carrier family 22 member 2, Organic cation transporter 2, hOCT2, SLC22A2
Purification Protein A/G purified from cell culture supernatant.
Accession O15244
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Solute carrier family 22 member 2 (SLC22A2/OCT2) is a ~62 kDa protein. Electrogenic voltage-dependent transporter that mediates the transport of a variety of organic cations such as endogenous bioactive amines, cationic drugs and xenobiotics. Functions as a Na(+)-independent, bidirectional uniporter. Cation cellular uptake or release is driven by the electrochemical potential, i.e. membrane potential and concentration gradient. However, may also engage electroneutral cation exchange when saturating concentrations of cation substrates are reached.

1. Gorboulev, V. et al. (1997) DNA and cell biology 16, 871-81. PMID: 9260930
2. Busch, AE. et al. (1998) Molecular pharmacology 54, 342-52. PMID: 9687576
3. Winter, TN. et al. (2011) Molecular pharmaceutics 8, 133-42. PMID: 21128598
4. Urakami, Y. et al. (2004) Pharmaceutical research 21, 976-81. PMID: 15212162
5. Kimura, N. et al. (2005) Pharmaceutical research 22, 255-9. PMID: 15783073
6. Amphoux, A. et al. (2006) Neuropharmacology 50, 941-52. PMID: 16581093
7. Taubert, D. et al. (2007) PloS one 2, e385. PMID: 17460754
Note For research use only.
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    SDS-PAGE

    SDS-PAGE for Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709)

References
Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709)

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