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| カタログ番号 | HF955014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SLC22A5 Polyclonal Antibody (HF955014) is a rabbit polyclonal antibody detecting SLC22A5 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLC22A5 (Thr45-Lys141). | ||||||||
| ターゲット | SLC22A5, Organic cation/carnitine transporter 2, High-affinity sodium-dependent carnitine cotransporter, OCTN2, Solute carrier family 22 member 5 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O76082 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Organic cation/carnitine transporter 2 (SLC22A5) is a ~62 kDa protein. Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 11.3. 1. Wu, X. et al. (1999) The Journal of pharmacology and experimental therapeutics 290, 1482-92. PMID: 10454528 2. Ohashi, R. et al. (1999) The Journal of pharmacology and experimental therapeutics 291, 778-84. PMID: 10525100 3. Wagner, CA. et al. (2000) American journal of physiology. Renal physiology 279, F584-91. PMID: 10966938 4. Maekawa, S. et al. (2007) Biochimica et biophysica acta 1773, 1000-6. PMID: 17509700 5. Fujiya, M. et al. (2011) Inflammatory bowel diseases 17, 907-16. PMID: 20722056 6. Yee, SW. et al. (2020) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34, 15734-15752. PMID: 33124720 7. Fujiya, M. et al. (2007) Cell host & microbe 1, 299-308. PMID: 18005709 | ||||||||
| 注意事項 | For research use only. |
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