

| Numéro de catalogue | HC027014 | ||||||||
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| Description |
Anti-Human SLC25A1 Polyclonal Antibody (HC027014) is a rabbit polyclonal antibody detecting mitochondrial; Citrate transport protein; CTP; Mitochondrial citrate carrier; CIC; Solute carrier family 25 member 1; Tricarboxylate carrier protein; SLC25A1; SLC20A3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human SLC25A1 (Glu47-Arg85&Glu106-Gly128&Glu144-Gln182&Leu241-Gly278). | ||||||||
| Cible | Tricarboxylate transport protein, mitochondrial; Citrate transport protein; CTP; Mitochondrial citrate carrier; CIC; Solute carrier family 25 member 1; Tricarboxylate carrier protein; SLC25A1; SLC20A3 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P53007 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Tricarboxylate transport protein, mitochondrial (SLC25A1) is a ~34 kDa protein. Mitochondrial electroneutral antiporter that exports citrate from the mitochondria into the cytosol in exchange for malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis-aconitate and to a lesser extent trans-aconitate, maleate and succinate. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. In the cytoplasm, citrate plays important roles in fatty acid and sterol synthesis, regulation of glycolysis, protein acetylation, and other physiopathological processes. 1. Chaouch, A. et al. (2014) Journal of neuromuscular diseases 1, 75-90. PMID: 26870663 2. Majd, H. et al. (2018) Biochimica et biophysica acta. Bioenergetics 1859, 1-7. PMID: 29031613 3. Pop, A. et al. (2018) Journal of inherited metabolic disease 41, 169-180. PMID: 29238895 4. Li, W. et al. (2025) The EMBO journal 44, 1641-1662. PMID: 39881208 5. Cimadamore-Werthein, C. et al. (2024) The EMBO journal 43, 3450-3465. PMID: 38937634 | ||||||||
| Note | For research use only |
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