

| Numéro de catalogue | HA253014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SLC29A1 Polyclonal Antibody (HA253014) is a rabbit polyclonal antibody detecting es-type; Solute carrier family 29 member 1; SLC29A1; ENT1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human SLC29A1 (Asn30-Asn82&Arg228-Val291). | ||||||||
| Cible | Equilibrative nucleoside transporter 1; hENT1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; es nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1; SLC29A1; ENT1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q99808 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Equilibrative nucleoside transporter 1 (SLC29A1) is a ~50 kDa protein. Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. 1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669 2. Lum, PY. et al. (2000) Cancer chemotherapy and pharmacology 45, 273-8. PMID: 10755314 3. Mangravite, LM. et al. (2003) American journal of physiology. Renal physiology 284, F902-10. PMID: 12527552 4. Endres, CJ. et al. (2004) The Biochemical journal 380, 131-7. PMID: 14759222 5. SenGupta, DJ. et al. (2004) Biochemical pharmacology 67, 453-8. PMID: 15037197 6. Visser, F. et al. (2007) The Journal of biological chemistry 282, 14148-57. PMID: 17379602 7. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683 8. Aseervatham, J. et al. (2015) PloS one 10, e0136779. PMID: 26406980 9. Huang, W. et al. (2017) Protein & cell 8, 284-295. PMID: 27995448 10. Niemann, B. et al. (2022) Nature 609, 361-368. PMID: 35790189 | ||||||||
| Note | For research use only |
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