Anti-Human SLC29A1/hENT1 Recombinant Antibody (SAA1893) (HA253013)

Name: Anti-Human SLC29A1/hENT1 Recombinant Antibody (SAA1893)
Brand: abinScience
SKU: HA253013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA253013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1893

Clonality

Monoclonal

Target

Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Solute carrier family 29 member 1, SLC29A1, Nucleoside transporter, es-type, Equilibrative NBMPR-sensitive nucleoside transporter, ENT1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99808

RRID

Anti-Human SLC29A1/hENT1 Antibody (SAA1893) (abinScience Cat# HA253013, RRID:AB_3727657)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Equilibrative nucleoside transporter 1 (SLC29A1/hENT1) is a ~50 kDa protein. Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier.

1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669

2. Lum, PY. et al. (2000) Cancer chemotherapy and pharmacology 45, 273-8. PMID: 10755314

3. Mangravite, LM. et al. (2003) American journal of physiology. Renal physiology 284, F902-10. PMID: 12527552

4. Endres, CJ. et al. (2004) The Biochemical journal 380, 131-7. PMID: 14759222

5. SenGupta, DJ. et al. (2004) Biochemical pharmacology 67, 453-8. PMID: 15037197

6. Visser, F. et al. (2007) The Journal of biological chemistry 282, 14148-57. PMID: 17379602

7. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683

8. Aseervatham, J. et al. (2015) PloS one 10, e0136779. PMID: 26406980

9. Huang, W. et al. (2017) Protein & cell 8, 284-295. PMID: 27995448

10. Niemann, B. et al. (2022) Nature 609, 361-368. PMID: 35790189

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human SLC29A1/hENT1 Antibody (SAA1893)

References

Datasheet

Anti-Human SLC29A1/hENT1 Recombinant Antibody (SAA1893).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC29A1/hENT1 Recombinant Antibody (SAA1893) (HA253013)

Overview

Images

References

Datasheet

SDS

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