Anti-Human SLC30A10 Polyclonal Antibody (HB363014)

Name: Anti-Human SLC30A10 Polyclonal Antibody
Brand: abinScience
SKU: HB363014
Price: 168 USD
Availability: InStock

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50ug
100ug

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Número de catálogo

HB363014

Descripción

Anti-Human SLC30A10 Polyclonal Antibody (HB363014) is a rabbit polyclonal antibody detecting Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human SLC30A10 (Lys300-Gly427).

Objetivo

Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q6XR72

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Calcium/manganese antiporter SLC30A10 is a ~52 kDa protein. Calcium:manganese antiporter of the plasma membrane mediating the efflux of intracellular manganese coupled to an active extracellular calcium exchange. Required for intracellular manganese homeostasis, an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. Manganese can also be cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Could also have an intracellular zinc ion transporter activity, directly regulating intracellular zinc ion homeostasis and more indirectly various signaling pathway and biological processes.

1. Levy, M. et al. (2019) The Journal of biological chemistry 294, 5879-5889. PMID: 30755481

2. Tuschl, K. et al. (2012) American journal of human genetics 90, 457-66. PMID: 22341972

3. Leyva-Illades, D. et al. (2014) The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 14079-95. PMID: 25319704

4. Zhao, Y. et al. (2016) Traffic (Copenhagen, Denmark) 17, 267-88. PMID: 26728129

5. Nishito, Y. et al. (2016) The Journal of biological chemistry 291, 14773-87. PMID: 27226609

6. Zogzas, CE. et al. (2016) The Journal of biological chemistry 291, 15940-57. PMID: 27307044

7. Patrushev, N. et al. (2012) PloS one 7, e33211. PMID: 22427991

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human SLC30A10 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human SLC30A10 Polyclonal Antibody (HB363014)

Vista general

Imágenes

Referencias

Datasheet

SDS