中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HB363014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SLC30A10 Polyclonal Antibody (HB363014) is a rabbit polyclonal antibody detecting Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC30A10 (Lys300-Gly427). | ||||||||
| ターゲット | Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q6XR72 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Calcium/manganese antiporter SLC30A10 is a ~52 kDa protein. Calcium:manganese antiporter of the plasma membrane mediating the efflux of intracellular manganese coupled to an active extracellular calcium exchange. Required for intracellular manganese homeostasis, an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. Manganese can also be cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Could also have an intracellular zinc ion transporter activity, directly regulating intracellular zinc ion homeostasis and more indirectly various signaling pathway and biological processes. 1. Levy, M. et al. (2019) The Journal of biological chemistry 294, 5879-5889. PMID: 30755481 2. Tuschl, K. et al. (2012) American journal of human genetics 90, 457-66. PMID: 22341972 3. Leyva-Illades, D. et al. (2014) The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 14079-95. PMID: 25319704 4. Zhao, Y. et al. (2016) Traffic (Copenhagen, Denmark) 17, 267-88. PMID: 26728129 5. Nishito, Y. et al. (2016) The Journal of biological chemistry 291, 14773-87. PMID: 27226609 6. Zogzas, CE. et al. (2016) The Journal of biological chemistry 291, 15940-57. PMID: 27307044 7. Patrushev, N. et al. (2012) PloS one 7, e33211. PMID: 22427991 | ||||||||
| 注意事項 | For research use only |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
