Anti-Human SLC30A10 Polyclonal Antibody (HB363014)

Name: Anti-Human SLC30A10 Polyclonal Antibody
Brand: abinScience
SKU: HB363014
Price: 168 USD
Availability: InStock

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Каталожный номер

HB363014

Описание

Anti-Human SLC30A10 Polyclonal Antibody (HB363014) is a rabbit polyclonal antibody detecting Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human SLC30A10 (Lys300-Gly427).

Цель

Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q6XR72

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Calcium/manganese antiporter SLC30A10 is a ~52 kDa protein. Calcium:manganese antiporter of the plasma membrane mediating the efflux of intracellular manganese coupled to an active extracellular calcium exchange. Required for intracellular manganese homeostasis, an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. Manganese can also be cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Could also have an intracellular zinc ion transporter activity, directly regulating intracellular zinc ion homeostasis and more indirectly various signaling pathway and biological processes.

1. Levy, M. et al. (2019) The Journal of biological chemistry 294, 5879-5889. PMID: 30755481

2. Tuschl, K. et al. (2012) American journal of human genetics 90, 457-66. PMID: 22341972

3. Leyva-Illades, D. et al. (2014) The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 14079-95. PMID: 25319704

4. Zhao, Y. et al. (2016) Traffic (Copenhagen, Denmark) 17, 267-88. PMID: 26728129

5. Nishito, Y. et al. (2016) The Journal of biological chemistry 291, 14773-87. PMID: 27226609

6. Zogzas, CE. et al. (2016) The Journal of biological chemistry 291, 15940-57. PMID: 27307044

7. Patrushev, N. et al. (2012) PloS one 7, e33211. PMID: 22427991

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Human SLC30A10 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human SLC30A10 Polyclonal Antibody (HB363014)

Обзор

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