

| Numéro de catalogue | HD570014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody (HD570014) is a rabbit polyclonal antibody detecting SLC6A2. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SLC6A2 NAT1 NET1 SLC6A5 (Phe167-Pro233&Ser363-Thr402&Pro570-Ile617). | ||||||||
| Cible | NAT1, NET, NET1, Norepinephrine transporter, SLC6A2, SLC6A5, Sodium-dependent noradrenaline transporter, Solute carrier family 6 member 2 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P23975 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Sodium-dependent noradrenaline transporter (SLC6A2 NAT1 NET1 SLC6A5) is a ~69 kDa protein. Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine re-uptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine. 1. Pacholczyk, T. et al. (1991) Nature 350, 350-4. PMID: 2008212 2. Gu, H. et al. (1994) The Journal of biological chemistry 269, 7124-30. PMID: 8125921 3. Zhang, H. et al. (2024) Nature 630, 247-254. PMID: 38750358 4. Syringas, M. et al. (2000) Molecular pharmacology 58, 1404-11. PMID: 11093780 5. Brown, CR. et al. (2025) Journal of neurochemistry 169, e16241. PMID: 39395208 6. Tan, J. et al. (2024) Nature 632, 921-929. PMID: 39048818 | ||||||||
| Note | For research use only |
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