

| Каталожный номер | HW576014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human SMARCA2 Polyclonal Antibody (HW576014) is a rabbit polyclonal antibody detecting SMARCA2. Suitable for Human, Rat, and Mouse.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human SMARCA2 (Lys725-Ser1179). | ||||||||
| Цель | BAF190B, BRG1-associated factor 190B, BRM, EC:3.6.4.-, Probable global transcription activator SNF2L2, Protein brahma homolog, SAMRCA2, SMARCA2, SNF2-alpha, SNF2A, SNF2L2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2, hBRM | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P51531 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Фон | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) is a ~181 kDa protein. ATPase involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. 1. Liu, K. et al. (2004) Genes & development 18, 673-86. PMID: 15075294 2. Euskirchen, G. et al. (2012) The Journal of biological chemistry 287, 30897-905. PMID: 22952240 3. Kadoch, C. et al. (2015) Science advances 1, e1500447. PMID: 26601204 | ||||||||
| Примечание | For research use only |



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