Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257) (HW576013)

Name: Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257)
Brand: abinScience
SKU: HW576013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HW576013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG1

Clone ID

SAA0257

Clonality

Monoclonal

Target

hBRM, SNF2A, Protein brahma homolog, SMARCA2, ATP-dependent helicase SMARCA2, SNF2-alpha, BRM, BAF190B, BRG1-associated factor 190B, Probable global transcription activator SNF2L2, SNF2L2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P51531

RRID

Anti-Human SMARCA2 IP Antibody (SAA0257) (abinScience Cat# HW576013, RRID:AB_3729791)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) is a ~181 kDa protein. ATPase involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.

1. Liu, K. et al. (2004) Genes & development 18, 673-86. PMID: 15075294

2. Euskirchen, G. et al. (2012) The Journal of biological chemistry 287, 30897-905. PMID: 22952240

3. Kadoch, C. et al. (2015) Science advances 1, e1500447. PMID: 26601204

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human SMARCA2 IP Antibody (SAA0257)

References

Datasheet

Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257) (HW576013)

Overview

Images

References

Datasheet

SDS

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