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Anti-Human Sortilin Recombinant Antibody (SAA0179) (HV066107)

Anti-Human Sortilin Recombinant Antibody (SAA0179)
Anti-Human Sortilin Recombinant Antibody (SAA0179)
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  • 概要

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  • データシート

  • SDS

概要
カタログ番号HV066107
種反応性Human
アプリケーションFCM
宿主種Human
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDSAA0179
ターゲット Neurotensin receptor 3, Gp95, Glycoprotein 95, Sortilin, 100 kDa NT receptor, NTR3, SORT1, NT3
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q99523
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Sortilin (SORT1/Gp95) is a ~92 kDa protein. Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. Also required for protein transport from the Golgi apparatus to the endosomes.

1. Ni, X. et al. (2006) Traffic (Copenhagen, Denmark) 7, 889-902. PMID: 16787399
注意事項 For research use only.
イメージ
  • Anti-Human Sortilin Recombinant Antibody (SAA0179)

    SDS-PAGE

    SDS-PAGE for Anti-Human Sortilin Recombinant Antibody (SAA0179)

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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