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Anti-Human SORT1/Gp95/Sortilin Recombinant Antibody (SAA0179), PerCP (HV066147)

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Aperçu
Numéro de catalogueHV066147
Reactivité des espècesHuman
ApplicationsFCM
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneSAA0179
ConjugaisonPerCP
Cible Neurotensin receptor 3, Gp95, Glycoprotein 95, Sortilin, 100 kDa NT receptor, NTR3, SORT1, NT3
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PerCP
Numéro d'accès Q99523
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Sortilin (SORT1/Gp95) is a ~92 kDa protein. Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. Also required for protein transport from the Golgi apparatus to the endosomes.

1. Ni, X. et al. (2006) Traffic (Copenhagen, Denmark) 7, 889-902. PMID: 16787399
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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C₂ (Working Conc.)
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