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| カタログ番号 | HP364023 | ||||||
|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||
| アプリケーション | ELISA, WB | ||||||
| 宿主種 | Rabbit | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG | ||||||
| クローンID | SAA2400 | ||||||
| ターゲット | Metalloreductase STEAP4, EC:1.16.1.-, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor alpha-induced protein 9, STEAP4, STAMP2, TNFAIP9 | ||||||
| エンドトキシンレベル | <10 EU/mg | ||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | Q687X5 | ||||||
| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Metalloreductase STEAP4 is a ~51 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance. 1. Oosterheert, W. et al. (2018) Nature communications 9, 4337. PMID: 30337524 2. Arner, P. et al. (2008) The Journal of clinical endocrinology and metabolism 93, 2249-54. PMID: 18381574 3. Zhang, CM. et al. (2008) Acta pharmacologica Sinica 29, 587-92. PMID: 18430367 4. Inoue, A. et al. (2009) Arthritis research & therapy 11, R118. PMID: 19660107 5. Tamura, T. et al. (2009) International journal of molecular medicine 24, 599-604. PMID: 19787193 | ||||||
| 注意事項 | For research use only |
SDS-PAGE for Anti-Human STEAP4 Antibody (SAA2400)
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