Anti-Human STIM1 Recombinant Antibody (SAA1741) (HC687013)

Name: Anti-Human STIM1 Recombinant Antibody (SAA1741)
Brand: abinScience
SKU: HC687013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC687013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1741

Objetivo

STIM1, Stromal interaction molecule 1, GOK

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q13586

RRID

Anti-Human STIM1 Antibody (SAA1741) (abinScience Cat# HC687013, RRID:AB_3727502)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Stromal interaction molecule 1 (STIM1) is a ~77 kDa protein. Acts as a Ca(2+) sensor that gates two major inward rectifying Ca(2+) channels at the plasma membrane: Ca(2+) release-activated Ca(2+) (CRAC) channels and arachidonate-regulated Ca(2+)-selective (ARC) channels. Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates CRAC channel pore-forming subunits ORA1, ORA2 and ORAI3 to generate sustained and oscillatory Ca(2+) entry. Involved in enamel formation.

1. Roos, J. et al. (2005) The Journal of cell biology 169, 435-45. PMID: 15866891

2. Liou, J. et al. (2005) Current biology : CB 15, 1235-41. PMID: 16005298

3. Zhang, SL. et al. (2005) Nature 437, 902-5. PMID: 16208375

4. Spassova, MA. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 4040-5. PMID: 16537481

5. Peinelt, C. et al. (2006) Nature cell biology 8, 771-3. PMID: 16733527

6. Soboloff, J. et al. (2006) The Journal of biological chemistry 281, 20661-20665. PMID: 16766533

7. Mercer, JC. et al. (2006) The Journal of biological chemistry 281, 24979-90. PMID: 16807233

8. Stathopulos, PB. et al. (2008) Cell 135, 110-22. PMID: 18854159

9. Yuan, JP. et al. (2009) Nature cell biology 11, 337-43. PMID: 19182790

10. Park, CY. et al. (2009) Cell 136, 876-90. PMID: 19249086

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human STIM1 Antibody (SAA1741)

Referencias

Datasheet

Anti-Human STIM1 Recombinant Antibody (SAA1741).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo