Anti-Human SYK Recombinant Antibody (SAA1636) (HW747013)

Name: Anti-Human SYK Recombinant Antibody (SAA1636)
Brand: abinScience
SKU: HW747013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HW747013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1636

Objetivo

Spleen tyrosine kinase, SYK, Tyrosine-protein kinase SYK, p72-Syk

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P43405

RRID

Anti-Human SYK Antibody (SAA1636) (abinScience Cat# HW747013, RRID:AB_3727397)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Tyrosine-protein kinase SYK is a ~72 kDa protein. Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor.

1. Urzainqui, A. et al. (2002) Immunity 17, 401-12. PMID: 12387735

2. Wang, L. et al. (2021) Nature genetics 53, 500-510. PMID: 33782605

3. Chiu, CW. et al. (2002) The EMBO journal 21, 6461-72. PMID: 12456653

4. Shim, EK. et al. (2004) FEBS letters 575, 35-40. PMID: 15388330

5. M Gagné, L. et al. (2021) The Journal of biological chemistry 297, 101291. PMID: 34634301

6. Law, CL. et al. (1996) Molecular and cellular biology 16, 1305-15. PMID: 8657103

7. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human SYK Antibody (SAA1636)

Referencias

Datasheet

Anti-Human SYK Recombinant Antibody (SAA1636).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo