Anti-Human SYK Recombinant Antibody (SAA1636) (HW747013)

Name: Anti-Human SYK Recombinant Antibody (SAA1636)
Brand: abinScience
SKU: HW747013
Price: 196 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW747013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1636

Cible

Spleen tyrosine kinase, SYK, Tyrosine-protein kinase SYK, p72-Syk

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P43405

RRID

Anti-Human SYK Antibody (SAA1636) (abinScience Cat# HW747013, RRID:AB_3727397)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Tyrosine-protein kinase SYK is a ~72 kDa protein. Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor.

1. Urzainqui, A. et al. (2002) Immunity 17, 401-12. PMID: 12387735

2. Wang, L. et al. (2021) Nature genetics 53, 500-510. PMID: 33782605

3. Chiu, CW. et al. (2002) The EMBO journal 21, 6461-72. PMID: 12456653

4. Shim, EK. et al. (2004) FEBS letters 575, 35-40. PMID: 15388330

5. M Gagné, L. et al. (2021) The Journal of biological chemistry 297, 101291. PMID: 34634301

6. Law, CL. et al. (1996) Molecular and cellular biology 16, 1305-15. PMID: 8657103

7. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human SYK Antibody (SAA1636)

Reférences

Fiche technique

Anti-Human SYK Recombinant Antibody (SAA1636).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai