Anti-Human SYK Recombinant Antibody (SAA1636) (HW747013)

Name: Anti-Human SYK Recombinant Antibody (SAA1636)
Brand: abinScience
SKU: HW747013
Price: 196 USD
Availability: InStock

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Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HW747013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1636

Цель

Spleen tyrosine kinase, SYK, Tyrosine-protein kinase SYK, p72-Syk

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P43405

RRID

Anti-Human SYK Antibody (SAA1636) (abinScience Cat# HW747013, RRID:AB_3727397)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Tyrosine-protein kinase SYK is a ~72 kDa protein. Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor.

1. Urzainqui, A. et al. (2002) Immunity 17, 401-12. PMID: 12387735

2. Wang, L. et al. (2021) Nature genetics 53, 500-510. PMID: 33782605

3. Chiu, CW. et al. (2002) The EMBO journal 21, 6461-72. PMID: 12456653

4. Shim, EK. et al. (2004) FEBS letters 575, 35-40. PMID: 15388330

5. M Gagné, L. et al. (2021) The Journal of biological chemistry 297, 101291. PMID: 34634301

6. Law, CL. et al. (1996) Molecular and cellular biology 16, 1305-15. PMID: 8657103

7. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human SYK Antibody (SAA1636)

Ссылки

Даташит

Anti-Human SYK Recombinant Antibody (SAA1636).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа