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| カタログ番号 | HY096014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human TDGF1/CRIPTO Polyclonal Antibody (HY096014) is a rabbit polyclonal antibody detecting CRIPTO in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TDGF1/CRIPTO (Leu31-Thr172). | ||||||||
| ターゲット | Cripto-1 growth factor, Teratocarcinoma-derived growth factor 1, TDGF1, CRIPTO, Epidermal growth factor-like cripto protein CR1, CRGF | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P13385 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein Cripto (TDGF1) is a ~21 kDa protein. GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. 1. Lee, GH. et al. (2016) The Journal of cell biology 215, 705-718. PMID: 27881714 2. Bianco, C. et al. (2002) Molecular and cellular biology 22, 2586-97. PMID: 11909953 | ||||||||
| 注意事項 | For research use only. |
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