Anti-Human TDGF1/Cripto-1 Reference Antibody (BIIB015, RUO) (HY096016)

Name: Anti-Human TDGF1/Cripto-1 Reference Antibody (BIIB015, RUO)
Brand: abinScience
SKU: HY096016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HY096016
Description	Anti-Human TDGF1/CRIPTO (BIIB015) (HY096016) is a research-grade recombinant antibody targeting Cripto-1 growth factor. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG
Clone ID	BIIB015
Expression system	Mammalian cells
Target	Cripto-1 growth factor, Teratocarcinoma-derived growth factor 1, TDGF1, CRIPTO, Epidermal growth factor-like cripto protein CR1, CRGF
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P13385
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BIIB015
Background	Protein Cripto (TDGF1) is a ~21 kDa protein. GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. 1. Lee, GH. et al. (2016) The Journal of cell biology 215, 705-718. PMID: 27881714 2. Bianco, C. et al. (2002) Molecular and cellular biology 22, 2586-97. PMID: 11909953
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human TDGF1/CRIPTO (BIIB015)

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Datasheet

Anti-Human TDGF1/Cripto-1 Reference Antibody (BIIB015, RUO).pdf

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Anti-Human TDGF1/Cripto-1 Reference Antibody (BIIB015, RUO) (HY096016)

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