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Anti-Human TMPRSS6 Recombinant Antibody (REGN7999) (HA025033)

Anti-Human TMPRSS6 Recombinant Antibody (REGN7999)
Anti-Human TMPRSS6 Recombinant Antibody (REGN7999)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
Contáctenos
  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHA025033
Reactividad de especiesHuman
AplicacionesELISA, FCM
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG4, kappa
ID de clonREGN7999
Objetivo Transmembrane protease serine 6, EC:3.4.21.-, Matriptase-2, TMPRSS6
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q8IU80
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Transmembrane protease serine 6 (TMPRSS6) is a ~90 kDa protein. Membrane-bound serine protease. Through the cleavage of cell surface hemojuvelin (HJV), a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.

1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966
2. Stirnberg, M. et al. (2010) The Biochemical journal 430, 87-95. PMID: 20518742
3. De Falco, L. et al. (2014) Human mutation 35, 1321-9. PMID: 25156943
4. McDonald, CJ. et al. (2015) American journal of physiology. Cell physiology 308, C539-47. PMID: 25588876
5. Finberg, KE. et al. (2008) Nature genetics 40, 569-71. PMID: 18408718
Nota For research use only
Imágenes
  • Anti-Human TMPRSS6 Recombinant Antibody (REGN7999)

    SDS-PAGE

    SDS-PAGE for Anti-Human TMPRSS6 Antibody (REGN7999)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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