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Anti-Human Matriptase 2 Reference Antibody (Exerenibart, RUO) (HA025016)

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Anti-Human Matriptase 2 Reference Antibody (Exerenibart, RUO)

Anti-Human Matriptase 2 Reference Antibody (Exerenibart, RUO)

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SDS

Overview

Catalog No.	HA025016
Description	exerenibart (HA025016) is a research-grade recombinant antibody targeting TMPRSS6. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4, Kappa
Species	Human
Clonality	Monoclonal
Target	TMPRSS6
Purity	>95% as determined by SDS-PAGE.
Accession	Q8IU80
Form	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2996101-49-4
Background	Transmembrane protease serine 6 (TMPRSS6) is a ~90 kDa protein. Membrane-bound serine protease. Through the cleavage of cell surface hemojuvelin (HJV), a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis. 1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966 2. Stirnberg, M. et al. (2010) The Biochemical journal 430, 87-95. PMID: 20518742 3. De Falco, L. et al. (2014) Human mutation 35, 1321-9. PMID: 25156943 4. McDonald, CJ. et al. (2015) American journal of physiology. Cell physiology 308, C539-47. PMID: 25588876 5. Finberg, KE. et al. (2008) Nature genetics 40, 569-71. PMID: 18408718
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade exerenibart

References

Datasheet

Anti-Human Matriptase 2 Reference Antibody (Exerenibart, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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Stock Solution

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Working Solution

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Anti-Human Matriptase 2 Reference Antibody (Exerenibart, RUO)