Anti-Human TMPRSS6 Recombinant Antibody (REGN7999) (HA025033)

Name: Anti-Human TMPRSS6 Recombinant Antibody (REGN7999)
Brand: abinScience
SKU: HA025033
Price: 191 USD
Availability: InStock

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Price(USD): $

Spec:

50ug
100ug
1mg

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA025033

Species reactivity

Human

Applications

ELISA, FCM

Host species

Human

Isotype

IgG4, kappa

Clone ID

REGN7999

Clonality

Monoclonal

Target

Transmembrane protease serine 6, EC:3.4.21.-, Matriptase-2, TMPRSS6

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8IU80

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Transmembrane protease serine 6 (TMPRSS6) is a ~90 kDa protein. Membrane-bound serine protease. Through the cleavage of cell surface hemojuvelin (HJV), a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.

1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966

2. Stirnberg, M. et al. (2010) The Biochemical journal 430, 87-95. PMID: 20518742

3. De Falco, L. et al. (2014) Human mutation 35, 1321-9. PMID: 25156943

4. McDonald, CJ. et al. (2015) American journal of physiology. Cell physiology 308, C539-47. PMID: 25588876

5. Finberg, KE. et al. (2008) Nature genetics 40, 569-71. PMID: 18408718

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Human TMPRSS6 Antibody (REGN7999)

References

Datasheet

Anti-Human TMPRSS6 Recombinant Antibody (REGN7999).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TMPRSS6 Recombinant Antibody (REGN7999) (HA025033)

Overview

Images

References

Datasheet

SDS

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