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Anti-Human TRIM31 Polyclonal Antibody (HP111024)

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Vista general
Número de catálogoHP111024
Descripción
Anti-Human TRIM31 Polyclonal Antibody (HP111024) is a rabbit polyclonal antibody detecting TRIM31. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human TRIM31 (Met1-Gln145).
Objetivo C6orf13, E3 ubiquitin-protein ligase TRIM31, EC:2.3.2.27, RNF, TRIM31, Tripartite motif-containing protein 31
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q9BZY9
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

E3 ubiquitin-protein ligase TRIM31 is a ~48 kDa protein. E3 ubiquitin-protein ligase that acts as a regulator of antiviral immune response and inflammation by mediating ubiquitination of substrates. Acts as a regulator of innate immune defense against viruses by mediating 'Lys-63'-linked ubiquitination of MAVS, promoting MAVS polymerization and formation of three-stranded helical filaments on mitochondria. Acts as a negative regulator of the NLRP3 inflammasome by catalyzing 'Lys-48'-linked ubiquitination of NLRP3, leading to its degradation. Regulator of Src-induced anchorage independent cell growth.

1. Sugiura, T. et al. (2008) Journal of cellular biochemistry 105, 1081-91. PMID: 18773414
2. Song, H. et al. (2016) Nature communications 7, 13727. PMID: 27929086
3. Liu, B. et al. (2017) Nature immunology 18, 214-224. PMID: 27992402
Nota For research use only
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Formula
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