

| カタログ番号 | HP145024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human TRIM33 Polyclonal Antibody (HP145024) is a rabbit polyclonal antibody detecting TRIM33 in ELISA, IHC, WB. Suitable for Human, Mouse, and Xenopus laevis.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TRIM33 (Lys141-Arg535). | ||||||||
| ターゲット | TRIM33, RFG7, KIAA1113, RET-fused gene 7 protein, Tripartite motif-containing protein 33, RING-type E3 ubiquitin transferase TRIM33, E3 ubiquitin-protein ligase TRIM33, Protein Rfg7, TIF1-gamma, Ectodermin homolog, TIF1G, Transcription intermediary factor 1-gamma | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9UPN9 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | E3 ubiquitin-protein ligase TRIM33 is a ~122 kDa protein. Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. 1. He, W. et al. (2006) Cell 125, 929-41. PMID: 16751102 | ||||||||
| 注意事項 | For research use only. |
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