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Anti-Human TRPV1 Recombinant Antibody (SAA1705) (HV711013)

Anti-Human TRPV1 Recombinant Antibody (SAA1705)
Anti-Human TRPV1 Recombinant Antibody (SAA1705)
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Especificación:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoHV711013
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA1705
Objetivo VR1, Vanilloid receptor 1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, Osm-9-like TRP channel 1, TrpV1, TRPV1, OTRPC1
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q8NER1
RRID Anti-Human TRPV1 Antibody (SAA1705) (abinScience Cat# HV711013, RRID:AB_3727466)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a ~94 kDa protein. Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activated by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius.

1. Hayes, P. et al. (2000) Pain 88, 205-215. PMID: 11050376
2. Cortright, DN. et al. (2001) Biochemical and biophysical research communications 281, 1183-9. PMID: 11243859
3. McIntyre, P. et al. (2001) British journal of pharmacology 132, 1084-94. PMID: 11226139
4. Smith, GD. et al. (2002) Nature 418, 186-90. PMID: 12077606
5. Neuberger, A. et al. (2023) Nature communications 14, 2451. PMID: 37117175
Nota For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Imágenes
  • Anti-Human TRPV1 Recombinant Antibody (SAA1705)

    SDS-PAGE

    SDS-PAGE for Anti-Human TRPV1 Antibody (SAA1705)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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