Anti-TRPV1 Polyclonal Antibody (HV711014)

Name: Anti-TRPV1 Polyclonal Antibody
Brand: abinScience
SKU: HV711014
Price: 168 USD
Availability: InStock

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Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV711014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TRPV1 (Met1-Glu153).

Target

VR1, Vanilloid receptor 1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, Osm-9-like TRP channel 1, TrpV1, TRPV1, OTRPC1

Purification

Purified by antigen affinity column.

Accession

Q8NER1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a ~94 kDa protein. Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activated by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius.

1. Hayes, P. et al. (2000) Pain 88, 205-215. PMID: 11050376

2. Cortright, DN. et al. (2001) Biochemical and biophysical research communications 281, 1183-9. PMID: 11243859

3. McIntyre, P. et al. (2001) British journal of pharmacology 132, 1084-94. PMID: 11226139

4. Smith, GD. et al. (2002) Nature 418, 186-90. PMID: 12077606

5. Neuberger, A. et al. (2023) Nature communications 14, 2451. PMID: 37117175

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-TRPV1 polyclonal antibody at 1ug/mL on recombinant TRPV1 (Catalog No. HV711012).

References

Datasheet

Anti-TRPV1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-TRPV1 Polyclonal Antibody (HV711014)

Overview

Images

References

Datasheet

SDS

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