

| Каталожный номер | HV711013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2a, kappa | ||||
| ID клона | SAA1705 | ||||
| Цель | VR1, Vanilloid receptor 1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, Osm-9-like TRP channel 1, TrpV1, TRPV1, OTRPC1 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q8NER1 | ||||
| RRID | Anti-Human TRPV1 Antibody (SAA1705) (abinScience Cat# HV711013, RRID:AB_3727466) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a ~94 kDa protein. Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activated by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius. 1. Hayes, P. et al. (2000) Pain 88, 205-215. PMID: 11050376 2. Cortright, DN. et al. (2001) Biochemical and biophysical research communications 281, 1183-9. PMID: 11243859 3. McIntyre, P. et al. (2001) British journal of pharmacology 132, 1084-94. PMID: 11226139 4. Smith, GD. et al. (2002) Nature 418, 186-90. PMID: 12077606 5. Neuberger, A. et al. (2023) Nature communications 14, 2451. PMID: 37117175 | ||||
| Примечание | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human TRPV1 Antibody (SAA1705)
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