Anti-Human TSC22D3 Polyclonal Antibody (HV509014)

Name: Anti-Human TSC22D3 Polyclonal Antibody
Brand: abinScience
SKU: HV509014
Price: 96 USD
Availability: InStock

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Обзор

Каталожный номер

HV509014

Описание

Anti-Human TSC22D3 Polyclonal Antibody (HV509014) is a rabbit polyclonal antibody detecting TSC22D3 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Macaca fascicularis, Mus musculus, Human, and Sus scrofa.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human TSC22D3 (Met1-Val134).

Цель

TSC22D3

Очистка

Purified by antigen affinity column.

Номер доступа

Q99576

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

TSC22 domain family protein 3, DSIP-immunoreactive peptide, Protein DIP, hDIP, Delta sleep-inducing peptide immunoreactor, Glucocorticoid-induced leucine zipper protein, GILZ, TSC-22-like protein, TSC-22-related protein, TSC-22R, TSC22D3, DSIPI, GILZ

Фон

TSC22 domain family protein 3 (TSC22D3) is a ~14 kDa protein. Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation and thereby NFKB1 DNA-binding activities. In vitro, suppresses AP-1 transcription factor complex DNA-binding activities.

1. Asselin-Labat, ML. et al. (2004) Blood 104, 215-23. PMID: 15031210

2. Berrebi, D. et al. (2003) Blood 101, 729-38. PMID: 12393603

3. Ayroldi, E. et al. (2001) Blood 98, 743-53. PMID: 11468175

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human TSC22D3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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